Controlled-Release Drug Delivery

Crosslink is leveraging its experience and patent portfolio in the field of electroactive polymers to develop a versatile means of delivering pharmaceutically active agents. Efforts to date have been being directed toward finding new drug delivery systems in which drug molecules in a polymer matrix can be delivered to a precise region of the body (e.g. skin tissue) while also controlling the rate and frequency of delivery.

Through the application of voltage to test devices, our researchers have shown the ability to controllably release a negatively charged drug in a single step (burst release, left), or in multiple stepwise fashion (step release, right).

This concept has also been extended toward the controlled release of positively charged drugs.

This controlled-release drug delivery system has the potential to extend to a wide variety of charged pharmaceutically active agents such as anesthetics, antiseptics, antimicrobial agents, or anti-inflammatory agents.

 

Want to learn more about the how Your Ideas and Our Innovation can work together?
Contact Crosslink Now.

 

Acknowledgement:
This research and development project was conducted by Crosslink and is made possible by a contract that was awarded and administered by the U.S. Army Medical Research & Materiel Command (USAMRMC) and the Telemedicine & Advanced Technology Research Center (TATRC), at Fort Detrick, MD under Contract Number: (USAMRMC W81XWH-10-2-0051).

Non-Endorsement Disclaimer:
"The views, opinions and/or findings contained in this research/presentation/publication are those of the author(s)/company and do not necessarily reflect the views of the Department of Defense and should not be construed as an official DoD/Army position, policy or decision unless so designated by other documentation. No official endorsement should be made."